Visualizing Capillary Beds

Engineering of In Vitro 3D Capillary Beds by Self-Directed Angiogenic Sprouting

In recent years, microfluidic systems have been used to study fundamental aspects of angiogenesis through the patterning of single-layered, linear or geometric vascular channels. In vivo, however, capillaries exist in complex, three-dimensional (3D) networks, and angiogenic sprouting occurs with a degree of unpredictability in all x,y,z planes. The ability to generate capillary beds in vitro th...

Surface densities of diaphragmed fenestrae and transendothelial channels in different murine capillary beds.

Fenestrated capillaries are provided with two types of regular discontinuities: fenestrae with negatively charged diaphragms, and transendothelial channels fitted with two diaphragms, of which the luminal one is uncharged. These structures are expected to affect macromolecular exchanges on the basis of size and charge. We have detected variations in the surface density of fenestrations and tran...

Functional capillary beds in the beating, KCl-arrested and KCl-arrested-perfused myocardium of the dog.

Flow through Packed Beds and Fluidized Beds

Chemical engineering operations commonly involve the use of packed and fluidized beds. These are devices in which a large surface area for contact between a liquid and a gas (absorption, distillation) or a solid and a gas or liquid (adsorption, catalysis) is obtained for achieving rapid mass and heat transfer, and particularly in the case of fluidized beds, catalytic chemical reactions. You wil...

Removal of triacylglycerols from chylomicrons and VLDL by capillary beds: the basis of lipoprotein remnant formation.

The triacylglycerol content of chylomicrons and VLDL (very-low-density lipoprotein) compete for the same lipolytic pathway in the capillary beds. Although chylomicron triacylglycerols appear to be the favoured substrate for lipoprotein lipase, VLDL particles compete in numbers. Methods to quantify the specific triacylglycerol removal from VLDL and chylomicrons may involve endogenous labelling o...